Increased risk of SSEs in bone-only metastatic breast cancer patients treated with zoledronic acid
نویسندگان
چکیده
منابع مشابه
Increased risk of SSEs in bone-only metastatic breast cancer patients treated with zoledronic acid
BACKGROUND Bone represents one of the most common sites to which breast cancer cells metastasize. Patients experience skeletal related adverse events (pathological fractures, spinal cord compressions, and irradiation for deteriorated pain on bone) even during treatment with zoledronic acid (ZA). Therefore, we conducted a retrospective cohort study to investigate the predictive factors for sympt...
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15 صفحه اولAtypical Subtrochanteric Femur Fracture in Patient with Metastatic Breast Cancer Treated with Zoledronic Acid
Several case series have suggested an association exists between atypical femoral subtrochanteric fractures and long-term use of bisphosphonates. It is thought that prolonged use of bisphosphonates may lead to adynamic, fragile bone. The radiologic features of atypical fractures include diffuse cortical thickening, transverse fracture, and beaking at the lateral subtrochanteric area. Atypical s...
متن کاملBone Scan Index Is a Prognostic Factor for Breast Cancer Patients with Bone Metastasis Being Treated with Zoledronic Acid
Bone scan index (BSI) has been used to quantify the spread of bone metastasis and be a prognostic indicator in prostate cancer with bone metastases. However, the utility of BSI in breast cancer patients with bone metastasis has not been yet established. We retrospectively reviewed 57 female breast cancer patients with osteoblastic/lytic combined type bone metastases and treated with zoledronic ...
متن کاملValidation of Therapeutic Response Assessment by Bone Scintigraphy in Patients with Bone-only Metastatic Breast Cancers during Zoledronic Acid Treatment: Comparison with Computed Tomography Assessment.
PURPOSE To validate the use of bone scintigraphy (BS) versus computed tomography (CT) for therapeutic monitoring in patients during treatment with zoledronic acid. MATERIALS AND METHODS Eleven patients with bone-only metastatic disease and being treated with zoledronic acid were included. The effects of therapies including chemotherapy and hormone therapy were evaluated in 25 separate examina...
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ژورنال
عنوان ژورنال: Journal of Bone Oncology
سال: 2017
ISSN: 2212-1374
DOI: 10.1016/j.jbo.2017.08.004